Hydrochloric Acid → HCID 58897789, compound

HRID 2357861Notes

Reaction equation

HRID 2357861 reaction equation
CO[CH:3]1[C:11]2[C:6](=[C:7]([P:12]([C:19]3[CH:27]=[CH:26][CH:25]=[C:24]4[C:20]=3[CH2:21][CH:22]([CH3:30])[CH:23]4OC)[C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)[CH:8]=[CH:9][CH:10]=2)[CH2:5][CH:4]1[CH3:31].Cl.CO>O>[CH3:30][C:22]1[CH2:21][C:20]2[C:24]([CH:23]=1)=[CH:25][CH:26]=[CH:27][C:19]=2[P:12]([C:7]1[CH:8]=[CH:9][CH:10]=[C:11]2[C:6]=1[CH2:5][C:4]([CH3:31])=[CH:3]2)[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 887MethanolHCID 58897807HCID 58897807, compound

Product 1

HCID 58897789HCID 58897789, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A mixture of 21.3 g (49.5 mmol) of crude bis(1-methoxy-2-methyl-2,3-dihydro-1H-inden-4-yl)(phenyl)phosphine, 100 ml of 16 M HCl, and 150 ml of methanol was refluxed for 5 hours. This mixture was cooled to ambient temperature, and 100 ml of water was added. The white precipitate that formed was filtered off and dried in vacuum. Yield, 15.0 g (82%) of a white solid.

Workup

  1. temperaturewas refluxed for 5 hours
  2. customThe white precipitate that formed
  3. filtrationwas filtered off
  4. customdried in vacuum
  5. customYield

Sources & evidence

ORD record
ord-3f41be3e51c0474ca4fb5473647983be
Source dataset
uspto-grants-2010_07
Patent number
US07763562B2

Reaction notes

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