Potassium Carbonate → HCID 11522793, compound

HRID 2358056Notes

Reaction equation

HRID 2358056 reaction equation
[CH3:1][S:2]([O:5][C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([CH:12]2[CH2:17][CH2:16][NH:15][CH2:14][CH2:13]2)[C:7]=1[F:18])(=[O:4])=[O:3].C(=O)([O-])[O-].[K+].[K+].Br[CH2:26][CH2:27][O:28][CH3:29]>C(#N)C>[CH3:1][S:2]([O:5][C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([CH:12]2[CH2:13][CH2:14][N:15]([CH2:26][CH2:27][O:28][CH3:29])[CH2:16][CH2:17]2)[C:7]=1[F:18])(=[O:3])=[O:4]

Participants

5

Reactant 3

HCID 11430Potassium CarbonateHCID 809722-Bromoethyl methyl etherHCID 57448046HCID 57448046, compound

Product 1

HCID 11522793HCID 11522793, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

Preparation according to Example 1: 2-fluoro-3-piperidin-4-ylphenyl methanesulfonate (0.01 g), acetonitrile (2 ml), potassium carbonate (0.01 g) and 1-bromo-2-methoxyethane (0.01 g). MS m/z (rel. intensity, 70 eV) 331 (M+, 1), 288 (6), 287 (15), 286 (bp), 207 (47).

Workup

  1. customPreparation

Sources & evidence

ORD record
ord-3e5b87a115ff4cc1be219a8929f7153f
Source dataset
uspto-grants-2010_07
Patent number
US07763639B2

Reaction notes

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