反应详情

To the solution of 6-3 (50 mg, 0.1 mmol) in 1 mL of DCM was added TFA (1 mL) and the mixture was stirred at room temperature for 3 h. The mixture was concentrated by evaporation and the residue was purified by prep.HPLC to give the product 6-4.

1. concentrationThe mixture was concentrated by evaporation
2. customthe residue was purified by prep.HPLC