Isobutanol → HCID 86682254, compound

HRID 2363249Notes

Reaction equation

HRID 2363249 reaction equation
[CH2:1]([OH:5])[CH:2]([CH3:4])[CH3:3].[C:6](Cl)(=[O:10])[C:7]([Cl:9])=[O:8]>>[CH2:1]([O:5][C:6](=[O:10])[C:7]([Cl:9])=[O:8])[CH:2]([CH3:4])[CH3:3]

Participants

3

Reactant 2

HCID 6560IsobutanolHCID 65578Oxalyl chloride

Product 1

HCID 86682254HCID 86682254, compound

Procedure

Isobutanol (191 μL, 2.1 mmol, 1.0 eq.) was added dropwise over 5 minutes to oxalyl chloride (350 μL, 4.14 mmol, 2.0 eq.) at 0° C., and the resulting mixture was stirred at room temperature for 2 hours. The excess oxalyl chloride was removed by rotary evaporation (40° C., 40 mmHg) and used without further purification.

Workup

  1. customThe excess oxalyl chloride was removed by rotary evaporation (40° C., 40 mmHg)
  2. customused without further purification

Sources & evidence

ORD record
ord-adb99a93c2774b8aa255178fe4e4a856
Source dataset
uspto-grants-2014_04
Patent number
US08691868B2

Reaction notes

Loading…