反应详情

To a solution of the intermediate of step E in methylene chloride (5 mL) was added 4 M HCl in dioxane (5 mL). After stirred at room temperature for 2 h, the resulting solution was concentrated in vacuo to give the HCl salt (350 mg) of the amine as a white solid. LCMS: (M+H)+ 364.4.

1. concentrationthe resulting solution was concentrated in vacuo