反应详情

1-(4-Fluorophenyl)-2-((2,3,6-trifluorobenzyl)sulfinyl)-1H-imidazole-5-carbaldehyde (33) was prepared in a similar manner as that described for the synthesis of compound 20 using 1-(4-fluorophenyl)-2-((2,3,6-trifluorobenzyl)thio)-1H-imidazole-5-carbaldehyde (32) (150 mg, 0.41 mmol), Oxone (629 mg, 1.02 mmol), acetone (4 mL) and 0.2M sodium bicarbonate (4 mL).