Methylamine → 6-Methoxy-N-methyl-3-nitropyridin-2-amine

HRID 2368657Notes

Reaction equation

HRID 2368657 reaction equation
Cl[C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][CH:5]=[C:4]([O:11][CH3:12])[N:3]=1.[CH3:13][NH2:14]>C1COCC1>[CH3:12][O:11][C:4]1[N:3]=[C:2]([NH:14][CH3:13])[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][CH:5]=1

Participants

4

Reactant 2

HCID 6329MethylamineHCID 27950292-Chloro-6-methoxy-3-nitropyridine

Product 1

HCID 30239146-Methoxy-N-methyl-3-nitropyridin-2-amine

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

Prepared analogously to example 154a from 2-chloro-6-methoxy-3-nitropyridine and 2 N methylamine (solution in THF) in THF

Sources & evidence

ORD record
ord-4e91caaac0074b0fb591220c34b99e6b
Source dataset
uspto-grants-2014_04
Patent number
US08703796B2

Reaction notes

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