Methylamine → 6-chloro-N-methyl-3-nitropyridin-2-amine

HRID 2368667Notes

Reaction equation

HRID 2368667 reaction equation
Cl[C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][CH:5]=[C:4]([Cl:11])[N:3]=1.[CH3:12][NH2:13]>C(O)C>[Cl:11][C:4]1[N:3]=[C:2]([NH:13][CH3:12])[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][CH:5]=1

Participants

4

Reactant 2

HCID 6329MethylamineHCID 852392,6-Dichloro-3-nitropyridine

Product 1

HCID 107500946-chloro-N-methyl-3-nitropyridin-2-amine

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Prepared analogously to example 154a from 2,6-dichloro-3-nitro-pyridine and methylamine (40% in water) in ethanol.

Sources & evidence

ORD record
ord-5863c077257343f9acb5f628a2848039
Source dataset
uspto-grants-2014_04
Patent number
US08703796B2

Reaction notes

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