反应详情

A solution of 2.91 g (14.39 mmol) of bromoacetyl bromide in 40 ml was cooled to 0° C. and 2.1 ml (14.39 mmol) of triethylamine and 2.64 g (14.39 mmol) of benzhydrylamine were successively added. The reaction solution was then evaporated to dryness under reduced pressure, and the resulting residue was purified on silica gel with EA as mobile phase. The product crystallized from the product fractions was filtered off with suction, washed with a little cold diethyl ether and dried under reduced pressure, resulting in 0.85 g of the title compound.

1. customThe reaction solution was then evaporated to dryness under reduced pressure
2. customthe resulting residue was purified on silica gel with EA as mobile phase
3. customThe product crystallized from the product fractions
4. filtrationwas filtered off with suction
5. washwashed with a little cold diethyl ether
6. customdried under reduced pressure