Hydrochloric Acid → HCID 19907590, compound

HRID 2371517Notes

Reaction equation

HRID 2371517 reaction equation
[C:1]([C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH:14]=[CH:13][C:12]([O:15][CH:16]([CH2:20][CH2:21][CH2:22][CH3:23])[C:17]([O-:19])=[O:18])=[CH:11][CH:10]=2)=[CH:5][CH:4]=1)#[N:2].[OH-].[K+].Cl>C(O)C>[C:1]([C:3]1[CH:4]=[CH:5][C:6]([C:9]2[CH:14]=[CH:13][C:12]([O:15][CH:16]([CH2:20][CH2:21][CH2:22][CH3:23])[C:17]([OH:19])=[O:18])=[CH:11][CH:10]=2)=[CH:7][CH:8]=1)#[N:2]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 14797Potassium HydroxideHCID 19907591HCID 19907591, compound

Product 1

HCID 19907590HCID 19907590, compoundYield 70%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

6.11 g (19 mmole) of 4-cyanobiphenyl-4'-oxy-hexanoate, 11 g potassium hydroxide and 100 ml absolute ethanol were stirred at room temperature for 3 hours, after which time the mixture was poured into 300 ml ice water. The resultant solution was neutralized with hydrochloric acid. The solids were filtered out, washed with water, and dried in a vacuum desiccator for 48 hours. After recrystallization from absolute ethanol, the resultant product (70% yield) had a melting point of 165° C.

Workup

  1. filtrationThe solids were filtered out
  2. washwashed with water
  3. customdried in a vacuum desiccator for 48 hours
  4. customAfter recrystallization from absolute ethanol

Sources & evidence

ORD record
ord-a6032892cacb47fd9b24a76026d667b1
Source dataset
uspto-grants-1992_03
Patent number
US05093471

Reaction notes

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