N-Methylpiperidine → HCID 19907488, compound

HRID 2371538Notes

Reaction equation

HRID 2371538 reaction equation
[Br:1][CH2:2][CH2:3][CH2:4][CH2:5][C:6]1[CH:11]=[CH:10][C:9]([CH2:12][CH2:13][CH2:14][CH2:15]Br)=[CH:8][CH:7]=1.[CH3:17][N:18]1[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19]1>C(O)C>[Br-:1].[Br-:1].[CH3:17][N+:18]1([CH2:2][CH2:3][CH2:4][CH2:5][C:6]2[CH:11]=[CH:10][C:9]([CH2:12][CH2:13][CH2:14][CH2:15][N+:18]3([CH3:17])[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19]3)=[CH:8][CH:7]=2)[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19]1

Participants

4

Reactant 2

HCID 12291N-MethylpiperidineHCID 15284075HCID 15284075, compound

Product 1

HCID 19907488HCID 19907488, compoundYield 171.1%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

First, 0.35 g of 1,4-bis(4-bromobutyl)benzene and 0.5 g of N-methylpiperidine were dissolved in 5 ml of absolute ethanol, the solution was refluxed for 9 hours, and evaporated under a reduced pressure. To the residue were added acetone and a small amount of ethanol, and the mixture was stirred at a room temperature for 30 minutes. The resulting crystal was filtered, washed with acetone and dried under a reduced pressure to obtain 0.47 g of the title compound as a colorless crystal.

Workup

  1. temperaturethe solution was refluxed for 9 hours
  2. customevaporated under a reduced pressure
  3. additionTo the residue were added acetone
  4. filtrationThe resulting crystal was filtered
  5. washwashed with acetone
  6. customdried under a reduced pressure

Sources & evidence

ORD record
ord-cca3eec2403c4236951c1c36de456516
Source dataset
uspto-grants-1992_03
Patent number
US05093370

Reaction notes

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