Acetone → HCID 19907368, compound

HRID 2371553Notes

Reaction equation

HRID 2371553 reaction equation
[CH2:1]([N:3]([CH2:25][CH3:26])[CH2:4][CH2:5][CH2:6][C:7]1[CH:16]=[CH:15][C:14]2[C:9](=[CH:10][CH:11]=[C:12]([CH2:17][CH2:18][CH2:19][N:20]([CH2:23][CH3:24])[CH2:21][CH3:22])[CH:13]=2)[CH:8]=1)[CH3:2].[CH2:27]([I:29])[CH3:28].[CH3:30][C:31](C)=O>C(O)C>[I-:29].[I-:29].[CH2:23]([N+:20]([CH2:27][CH3:28])([CH2:21][CH3:22])[CH2:19][CH2:18][CH2:17][C:12]1[CH:11]=[CH:10][C:9]2[C:14](=[CH:15][CH:16]=[C:7]([CH2:6][CH2:5][CH2:4][N+:3]([CH2:30][CH3:31])([CH2:1][CH3:2])[CH2:25][CH3:26])[CH:8]=2)[CH:13]=1)[CH3:24]

Participants

5

Reactant 3

HCID 180AcetoneHCID 6340IodoethaneHCID 19907346HCID 19907346, compound

Product 1

HCID 19907368HCID 19907368, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

To a solution of 78 mg of 2,6-bis(3-diethylaminopropyl)naphthalene in 1 ml of absolute ethanol was added 176 μl of ethyl iodide, and the mixture was refluxed for 140 minutes and cooled. After adding 2 ml of acetone, the mixture was stirred for 20 minutes. The resulting crystal was collected by filtration, washed with acetone and dried under a reduced pressure to obtain 117 mg of the title compound as a colorless crystal.

Workup

  1. temperaturethe mixture was refluxed for 140 minutes
  2. temperaturecooled
  3. filtrationThe resulting crystal was collected by filtration
  4. washwashed with acetone
  5. customdried under a reduced pressure

Sources & evidence

ORD record
ord-55c17812c60740b4bfc2feab140dd78e
Source dataset
uspto-grants-1992_03
Patent number
US05093370

Reaction notes

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