Dimethylformamide → HCID 19985186, compound

HRID 2371664Notes

Reaction equation

HRID 2371664 reaction equation
[CH2:1]([O:13][C:14]1[CH:22]=[CH:21][CH:20]=[CH:19][C:15]=1[C:16](O)=[O:17])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12].CN(C)C=O.S(Cl)([Cl:30])=O>C(Cl)Cl>[CH2:1]([O:13][C:14]1[CH:22]=[CH:21][CH:20]=[CH:19][C:15]=1[C:16]([Cl:30])=[O:17])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12]

Participants

5

Reactant 3

HCID 6228DimethylformamideHCID 24386Thionyl ChlorideHCID 289454Benzoic acid, 2-(dodecyloxy)-

Product 1

HCID 19985186HCID 19985186, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

29.1 g of the dodecyloxybenzoic acid was dissolved in 300 ml of methylene chloride, 1 ml of N,N-dimethylformamide was added, and 24 g of thionyl chloride was added dropwise over about 30 min under heating and reflux. After the addition the heating and refluxing were continued for 2 hours further, and concentration was conducted, to obtain 2-dodecyloxybenzoic acid chloride.

Workup

  1. temperatureunder heating
  2. temperaturereflux
  3. additionAfter the addition the heating and
  4. temperaturerefluxing
  5. concentrationfurther, and concentration

Sources & evidence

ORD record
ord-5478a2c45fc74b69a27fcc1927b2ff54
Source dataset
uspto-grants-1992_03
Patent number
US05094938

Reaction notes

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