Hydrochloric Acid → HCID 21694998, compound

HRID 2372316Notes

Reaction equation

HRID 2372316 reaction equation
[N:1]1[CH:6]=[CH:5][C:4]([CH2:7][N:8]2[C:12](=[O:13])[CH2:11][CH2:10][C:9]2=[O:14])=[CH:3][CH:2]=1.[ClH:15]>C(O)C.[Pt]=O>[ClH:15].[NH:1]1[CH2:2][CH2:3][CH:4]([CH2:7][N:8]2[C:12](=[O:13])[CH2:11][CH2:10][C:9]2=[O:14])[CH2:5][CH2:6]1

Participants

5

Reactant 2

HCID 313Hydrochloric AcidHCID 21695009HCID 21695009, compound

Product 1

HCID 21694998HCID 21694998, compound

Reagents, catalysts & solvents 2

HCID 82844Platinum oxide (PtO)CatalystHCID 702EthanolSolvent

Procedure

A suspension of platinum oxide (0.3 g), in a solution of XVII (16.71 g, 88 mmol) in ethanol (100 mL) and concentrated HCl (17.6 g, 176 mmol), was hydrogenated in a 500 mL Parr bottle at 60 psi and room temperature for 24 hr. The mixture was then filtered. The filtrate was concentrated in vacuo to give the product as a white powder which was used in the next step without further purification.

Workup

  1. filtrationThe mixture was then filtered
  2. concentrationThe filtrate was concentrated in vacuo

Sources & evidence

ORD record
ord-dba748de196e46ebaffaf1cd8552ac0f
Source dataset
uspto-grants-1992_03
Patent number
US05098904

Reaction notes

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