反应详情

To a solution of 100 mmoles of (4-benzyloxy benzoyl) hydrazine in 200 ml of 1-propanol, 100 mmoles of acrylonitrile are added and the mixture is heated for 24 hours at reflux. Then 50 mmoles of acrylonitrile are added and the heating is continued at reflux for 24 hours. After cooling, the product is filtered and crystallized in a water-ethanol mixture and 26 g (yield: 88%) of the expected product were obtained.

1. temperaturethe mixture is heated for 24 hours
2. temperatureat reflux
3. temperatureat reflux for 24 hours
4. temperatureAfter cooling
5. filtrationthe product is filtered
6. customcrystallized in a water-ethanol mixture