Hydrochloric Acid → Triisopropylsilyl chloride

HRID 2373722Notes

Reaction equation

HRID 2373722 reaction equation
[CH:1]([Si:4]([CH:10]([CH3:12])[CH3:11])([CH:7]([CH3:9])[CH3:8])OC)([CH3:3])[CH3:2].[ClH:13]>>[CH:1]([Si:4]([CH:10]([CH3:12])[CH3:11])([CH:7]([CH3:9])[CH3:8])[Cl:13])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 589230Triisopropylmethoxysilane

Product 1

HCID 139400Triisopropylsilyl chlorideYield 99%

Conditions

Temperature
20 °C

Procedure

A 500 ml-capacity, four-necked flask fitted with a stirrer, a thermometer and a Dimroth was charged with 37.7 g (0.2 moles) of triisopropylmethoxysilane. To the flask was then added 150 g of 35% hydrochloric acid, and the resulting mixture was stirred at 20° C. for 10 hours to effect the reaction. The resulting reaction solution was separated into the aqueous layer and the organic layer. The organic layer was distilled to afford 38 g of triisopropylchlorosilane as a fraction boiling at 78° C.-80° C./10 mm Hg (yield; 99%).

Workup

  1. customA 500 ml-capacity, four-necked flask fitted with a stirrer
  2. customthe reaction
  3. customThe resulting reaction solution
  4. customwas separated into the aqueous layer
  5. distillationThe organic layer was distilled

Sources & evidence

ORD record
ord-f20e4d408cff4fbfbd0c8118dca03797
Source dataset
uspto-grants-2008_12
Patent number
US07459577B2

Reaction notes

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