Dimethyl Sulfate →

HRID 2374101Notes

Reaction equation

HRID 2374101 reaction equation
[S:1]([O:6]C)([O:4][CH3:5])(=[O:3])=[O:2].[C:8](=[O:28])([O:10][C:11]1[C:12]([C:24]([CH3:27])([CH3:26])[CH3:25])=[N:13][N:14]([CH2:17][C:18]2[CH:23]=[CH:22]N=CC=2)[C:15]=1[NH2:16])[NH2:9]>C(OCC)(=O)C>[CH3:5][O:4][S:1]([O-:6])(=[O:3])=[O:2].[C:8](=[O:28])([O:10][C:11]1[C:12]([C:24]([CH3:25])([CH3:26])[CH3:27])=[N:13][N:14]([CH2:17][CH:18]2[CH:23]=[CH2+:22][CH:11]=[CH:15][N:14]2[CH3:17])[C:15]=1[NH2:16])[NH2:9]

Participants

3

Reactant 2

HCID 6497Dimethyl SulfateHCID 69222535HCID 69222535, compound

Product 0

No Product data yet.

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

0.38 g (3 mmol) of dimethyl sulfate was added to 0.69 g (2.4 mmol) of the product from Step 2.4 in 10 mL of ethyl acetate, and the mixture was allowed to agitate overnight. A viscous oil separated. The supernatant solution was decanted and discarded. The residue was used in the next step without further purification.

Workup

  1. customA viscous oil separated
  2. customThe supernatant solution was decanted
  3. customThe residue was used in the next step without further purification

Sources & evidence

ORD record
ord-6806e09280d14449b855da93d08a2919
Source dataset
uspto-grants-2008_12
Patent number
US07462204B2

Reaction notes

Loading…