Hydrochloric Acid → HCID 59854615, compound

HRID 2375309Notes

Reaction equation

HRID 2375309 reaction equation
C(OC(=O)[NH:7][CH2:8][CH2:9][CH2:10][N:11]1[C:16](=[O:17])[CH2:15][O:14][CH2:13][C:12]1=[O:18])(C)(C)C.Cl>CCOCC>[NH2:7][CH2:8][CH2:9][CH2:10][N:11]1[C:16](=[O:17])[CH2:15][O:14][CH2:13][C:12]1=[O:18]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 58882158HCID 58882158, compound

Product 1

HCID 59854615HCID 59854615, compoundYield 116%

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent2×

Procedure

To a solution of tert-butyl-3-(3,5-dioxomorpholin-4-yl)propylcarbamate (15 g) in dry ether (150 mL) was added a saturated solution of dry HCl (gas) in diethylether (300 mL) at 0° C. and the solution was then slowly warmed up to r.t. The precipitate obtained was filtered, washed with cold ether and dried under vacuum to give 11 g of the title compound (94%).

Workup

  1. customThe precipitate obtained
  2. filtrationwas filtered
  3. washwashed with cold ether
  4. customdried under vacuum

Sources & evidence

ORD record
ord-31b8be1eaba04ee99da25b53b7d6bb9a
Source dataset
uspto-grants-2008_12
Patent number
US07465736B2

Reaction notes

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