Hydrogen chloride-ethyl acetate → HCID 68920400, compound

HRID 2375547Notes

Reaction equation

HRID 2375547 reaction equation
[N+:1]([O:4][CH2:5][C:6]1[N:11]=[C:10]([CH3:12])[C:9]([O:13][C:14](=[O:25])[C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=2[O:21][C:22](=[O:24])[CH3:23])=[CH:8][CH:7]=1)([O-:3])=[O:2].C(OCC)(=O)C.[ClH:32]>C(OCC)(=O)C>[ClH:32].[N+:1]([O:4][CH2:5][C:6]1[N:11]=[C:10]([CH3:12])[C:9]([O:13][C:14](=[O:25])[C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=2[O:21][C:22](=[O:24])[CH3:23])=[CH:8][CH:7]=1)([O-:3])=[O:2]

Participants

4

Reactant 2

HCID 21866389Hydrogen chloride-ethyl acetateHCID 68920401HCID 68920401, compound

Product 1

HCID 68920400HCID 68920400, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

To a solution of 2-acetyloxybenzoic acid 6-(nitrooxymethyl)-2-methylpyridinyl ester (1 g, 2.88 mmoles) in ethyl acetate (20 ml) cooled at 0° C., a solution of ethyl acetate/HCl 5M is added dropwise under stirring. It is left for 1 hour at 0° C., then the temperature is let reach room values. The formed precipitate is filtered and washed with ethyl ether. 900 mg of solid product are obtained.

Workup

  1. filtrationThe formed precipitate is filtered
  2. washwashed with ethyl ether

Sources & evidence

ORD record
ord-19dc8e9d0be843928f2e192f6b323f45
Source dataset
uspto-grants-2008_12
Patent number
US07465803B2

Reaction notes

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