Acetic Acid → HCID 69277781, compound

HRID 2378520Notes

Reaction equation

HRID 2378520 reaction equation
C(O)(=[O:3])C.[F:5][C:6]([F:23])([F:22])[C:7]1[CH:21]=[CH:20][C:10]([CH2:11][S:12][C:13]2[CH:18]=[CH:17][C:16]([OH:19])=[CH:15][CH:14]=2)=[CH:9][CH:8]=1.OO.[OH2:26]>>[F:23][C:6]([F:5])([F:22])[C:7]1[CH:21]=[CH:20][C:10]([CH2:11][S:12]([C:13]2[CH:18]=[CH:17][C:16]([OH:19])=[CH:15][CH:14]=2)(=[O:3])=[O:26])=[CH:9][CH:8]=1

Participants

5

Reactant 4

HCID 176Acetic AcidHCID 784Hydrogen PeroxideHCID 962WaterHCID 23089558HCID 23089558, compound

Product 1

HCID 69277781HCID 69277781, compound

Conditions

Temperature
90 °C

Procedure

To a 15 ml of acetic acid solution of 2.23 g of 4-(4-trifluoromethylbenzylsulfanyl)phenol was added slowly, 2.5 ml of 30% hydrogen peroxide solution at approximately 80° C. The reaction mixture was stirred for 3 hours at 90° C., then poured into water, and the resulted precipitate was collected by filteration. After washing with water, the precipitate was dried by heating under the reduced pressure to produce 2.34 g of the desired product.

Workup

  1. customat approximately 80° C
  2. customthe resulted precipitate was collected by filteration
  3. washAfter washing with water
  4. customthe precipitate was dried
  5. temperatureby heating under the reduced pressure

Sources & evidence

ORD record
ord-48297c23f8614cf49ecc16a6c07d9cd8
Source dataset
uspto-grants-2008_12
Patent number
US07470803B2

Reaction notes

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