Hydrochloric Acid → HCID 9838760, compound

HRID 2379191Notes

Reaction equation

HRID 2379191 reaction equation
[NH2:1][CH2:2][CH:3]([C:5]1[CH:6]=[C:7]([CH:13]=[CH:14][C:15]=1[F:16])[NH:8][S:9]([CH3:12])(=[O:11])=[O:10])[OH:4].[ClH:17]>>[ClH:17].[NH2:1][CH2:2][CH:3]([C:5]1[CH:6]=[C:7]([CH:13]=[CH:14][C:15]=1[F:16])[NH:8][S:9]([CH3:12])(=[O:10])=[O:11])[OH:4]

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 9838761N-[3-(2-Amino-1-hydroxyethyl)-4-fluorophenyl]methanesulfonamide

Product 1

HCID 9838760HCID 9838760, compound

Procedure

(±)-3'-(2-Amino-1-hydroxyethyl)-4'-fluoromethanesulfonanilide (2.3 g) was treated with 20% ethanolic hydrochloric acid to give 2.4 g of (±)-3'-(2-amino-1-hydroxyethyl)-4'-fluoromethanesulfonanilide hydrochloride, m.p. 178°-181° C. Elementary analysis for C9H13FN2O3S.HCl. Calcd: C 37.96, H 4.96, N 9.84; Found: C 37.97, H 5.06, N 9.59.

Sources & evidence

ORD record
ord-008a1a7aecfd432ab6ca84e7a14ec9f2
Source dataset
uspto-grants-1994_11
Patent number
US05360822

Reaction notes

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