Hydrochloric Acid → HCID 18958071, compound

HRID 2379196Notes

Reaction equation

HRID 2379196 reaction equation
[NH2:1][CH2:2][CH:3]([C:5]1[CH:6]=[C:7]([CH:13]=[C:14]([F:16])[CH:15]=1)[NH:8][S:9]([CH3:12])(=[O:11])=[O:10])[OH:4].[ClH:17]>>[ClH:17].[NH2:1][CH2:2][CH:3]([C:5]1[CH:6]=[C:7]([CH:13]=[C:14]([F:16])[CH:15]=1)[NH:8][S:9]([CH3:12])(=[O:10])=[O:11])[OH:4]

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 15232561HCID 15232561, compound

Product 1

HCID 18958071HCID 18958071, compound

Procedure

The compound (0.70 g) obtained in Example 10 was treated with 20% ethanolic hydrochloric acid to give 0.72 g of (±)-3'-(2-amino-1-hydroxyethyl)-5'-fluoromethanesulfonanilide hydrochloride. M.p. 183°-186° C.

Sources & evidence

ORD record
ord-388d9d9b102a4922a5b1a15e43e20e40
Source dataset
uspto-grants-1994_11
Patent number
US05360822

Reaction notes

Loading…