Hydrochloric Acid → N-(6-aminoquinolin-5-yl)-2-(hexylthio)decanoic amide

HRID 2379621Notes

Reaction equation

HRID 2379621 reaction equation
[NH:1]([C:5]1[C:6]([NH:15][C:16](=[O:33])[CH:17]([S:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH3:32])[CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH3:25])=[C:7]2[C:12](=[CH:13][CH:14]=1)[N:11]=[CH:10][CH:9]=[CH:8]2)C(C)=O.Cl>C(O)(C)C>[NH2:1][C:5]1[C:6]([NH:15][C:16](=[O:33])[CH:17]([S:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH3:32])[CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH3:25])=[C:7]2[C:12](=[CH:13][CH:14]=1)[N:11]=[CH:10][CH:9]=[CH:8]2

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 19027809HCID 19027809, compound

Product 1

HCID 19027894N-(6-aminoquinolin-5-yl)-2-(hexylthio)decanoic amide

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

N-(6-Acetaminoquinolin-5-yl)-2-(hexylthio)decanoic amide, prepared as described in Example 151, was treated with aqueous hydrochloric acid and isopropanol to give the title compound. Mass spectrum m/e: 428.3 (M+-1).

Sources & evidence

ORD record
ord-362493da281c46db957f3a74944d0472
Source dataset
uspto-grants-1994_11
Patent number
US05362878

Reaction notes

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