Hydrochloric Acid → HCID 14534035, compound

HRID 2379660Notes

Reaction equation

HRID 2379660 reaction equation
[C:1]1([CH3:11])[CH:6]=[CH:5][C:4]([S:7](Cl)(=[O:9])=[O:8])=[CH:3][CH:2]=1.[CH3:12][O:13][CH:14]([CH3:20])[CH2:15][CH2:16][CH2:17][CH2:18][OH:19].O.Cl>N1C=CC=CC=1>[CH3:12][O:13][CH:14]([CH3:20])[CH2:15][CH2:16][CH2:17][CH2:18][O:19][S:7]([C:4]1[CH:5]=[CH:6][C:1]([CH3:11])=[CH:2][CH:3]=1)(=[O:9])=[O:8]

Participants

6

Reactant 4

HCID 313Hydrochloric AcidHCID 962WaterHCID 73974-Toluenesulfonyl chlorideHCID 14534034HCID 14534034, compound

Product 1

HCID 14534035HCID 14534035, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent2×

Procedure

A solution of 1.83 g (9.6 mmol) of p-toluenesulfonic acid chloride in 5 ml of pyridine was added dropwise to a solution of 1.06 g (8.0 mmol) of 5-methoxyhexanol in 5 ml of pyridine below 5° C. on an iced water bath. After stirring for 6 hours at room temperature, the reaction mixture was injected into 100 ml of cold water and, after being acidified with 6N-hydrochloric acid, was extracted with isopropyl ether. The organic layer was washed with water and dried with anhydrous magnesium sulfate, followed by distilling-off of the solvent to obtain 5-methoxyhexyl-p-toluenesulfonate.

Workup

  1. extractionwas extracted with isopropyl ether
  2. washThe organic layer was washed with water
  3. dry with materialdried with anhydrous magnesium sulfate

Sources & evidence

ORD record
ord-3dbbb8ae4db44ac3bcfdc49e6b8f8ccf
Source dataset
uspto-grants-1994_11
Patent number
US05364559

Reaction notes

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