2,4-Difluoroaniline → HCID 86748284, compound

HRID 2380487Notes

Reaction equation

HRID 2380487 reaction equation
[CH2:1]([C:13]1[N:14]=[N:15][N:16]([CH:18]([C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)[C:19](O)=[O:20])[N:17]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12].C(C1[N:39]=NN(CC(O)=O)N=1)CCCCCCCCC.[F:47][C:48]1[CH:54]=[C:53]([F:55])[CH:52]=[CH:51][C:49]=1N.C(C1C=CC=C(C(C)C)C=1N)(C)C>>[F:47][C:48]1[CH:54]=[C:53]([F:55])[CH:52]=[CH:51][C:49]=1[C:18]([C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1)([N:16]1[N:15]=[N:14][C:13]([CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12])=[N:17]1)[C:19]([NH2:39])=[O:20]

Participants

5

Reactant 4

HCID 97092,4-DifluoroanilineHCID 32484DiisopropylanilineHCID 10523338(+/-)-5-dodecyl-alpha-phenyl-2H-tetrazole-2-acetic acidHCID 214695295-decyl-2H-tetrazole-2-acetic acid

Product 1

HCID 86748284HCID 86748284, compound

Procedure

When in the general procedure of Example 88 an appropriate amount of (±)-5-dodecyl-α-phenyl-2H-tetrazole-2-acetic acid was substituted for 5-decyl-2H-tetrazole-2-acetic acid and 2,4-difluoroaniline was substituted for 2,6-diisopropylaniline, the title compound was obtained, mp 62°-64° C.

Sources & evidence

ORD record
ord-6f1935fca4d046ee92a13e8cfe99423b
Source dataset
uspto-grants-1994_11
Patent number
US05366987

Reaction notes

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