反应详情

2.50 g (9.33 mmol) of 2-(3-bromopropyl)-1H-isoindole-1,3(2H)-dione in 25 ml of xylene were degassed with argon, and 2.45 g (9.33 mmol) of triphenylphosphine were added. The mixture was stirred under reflux for 24 h and then filtered at 70° C. The filter cake was washed with a little di-ethyl ether and dried under high vacuum. This gave 3.50 g (70.8% of theory) of the title compound.

1. additionwere added
2. temperatureunder reflux for 24 h
3. filtrationfiltered at 70° C
4. washThe filter cake was washed with a little di-ethyl ether
5. customdried under high vacuum