HCID 57828142, compound → HCID 57828147, compound

HRID 2386210Notes

Reaction equation

HRID 2386210 reaction equation
C([O:8][C:9]1[C:10]2[CH2:11][N:12]([CH2:32][C:33]([OH:35])=[O:34])[CH2:13][CH2:14][N:15]([CH2:28][C:29]([OH:31])=[O:30])[CH2:16][CH2:17][N:18]([CH2:24][C:25]([OH:27])=[O:26])[CH2:19][C:20]([N:23]=2)=[CH:21][CH:22]=1)C1C=CC=CC=1>Cl>[C:29]([CH2:28][N:15]1[CH2:14][CH2:13][N:12]([CH2:32][C:33]([OH:35])=[O:34])[CH2:11][C:10]2=[N:23][C:20](=[CH:21][CH:22]=[C:9]2[OH:8])[CH2:19][N:18]([CH2:24][C:25]([OH:27])=[O:26])[CH2:17][CH2:16]1)([OH:31])=[O:30]

Participants

3

Reactant 1

HCID 57828142HCID 57828142, compound

Product 1

HCID 57828147HCID 57828147, compound

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

8 g (0.0170 mol) of (12-benzyloxy-6,9-bis(carboxymethyl)-3,6,9,15-tetraazabicyclo[9.3.1]pentadeca-1(14),11(15),12-trien-3-yl)acetic acid are added to 100 ml of 10N HCl. The mixture is left to react overnight at 40° C. It is concentrated. The product is crystallized from acetone. w=6 g.

Workup

  1. waitThe mixture is left
  2. customto react overnight at 40° C
  3. concentrationIt is concentrated
  4. customThe product is crystallized from acetone

Sources & evidence

ORD record
ord-d0c912e73ceb4778886828ed54a8555b
Source dataset
uspto-grants-2012_09
Patent number
US08268810B2

Reaction notes

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