反应详情

温度

70 °C

Concentrated sulfuric acid (0.3 mL) was added to a solution of the product from step (v) (0.09 g) in MeOH (1 mL). The solution was heated at 70° C. for 3 h and then poured into saturated aqueous NaHCO3 solution (10 mL). The aqueous was extracted with EtOAC and the combined organic phases were dried, filtered and evaporated. The crude product was purified by RPHPLC to give the title compound, 0.007 g.

1. extractionThe aqueous was extracted with EtOAC
2. customthe combined organic phases were dried
3. filtrationfiltered
4. customevaporated
5. customThe crude product was purified by RPHPLC