反应详情

A mixture of the crude product from step (i) and guanidine (16 g) in EtOH (350 ml) was heated under reflux for 5 h. The mixture was cooled, neutralised with acetic acid, and the solid filtered and dried, 22.1 g.

1. temperaturewas heated
2. temperatureunder reflux for 5 h
3. temperatureThe mixture was cooled
4. filtrationthe solid filtered
5. customdried