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HRID2388357

反应详情

EQUATION

反应方程式

HRID 2388357 的结构方程式

REACTANTS

反应物

3
结构：CCN=C=NCCCN(C)C
HCID15908

1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimide

C8H17N3

结构：O=C(O)CNC(=O)c1cccc(C(F)(F)F)c1
HCID2777432

N-{Hydroxy[3-(trifluoromethyl)phenyl]methylidene}glycine

C10H8F3NO3

结构：NC1CN(C2CCC(c3noc(C(Cl)(Cl)Cl)n3)CC2)C1
HCID59541822

未命名化合物

PRODUCTS

生成物

1
结构：O=C(CNC(=O)c1cccc(C(F)(F)F)c1)NC1CN(C2CCC(c3noc(C(Cl)(Cl)Cl)n3)CC2)C1
HCID46946854

未命名化合物

PROCEDURE

实验过程

The title compound was prepared by the EDCI coupling of 1-[4-(5-trichloromethyl-[1,2,4]oxadiazol-3-yl)-cyclohexyl]-azetidin-3-ylamine (as prepared in the previous step) and (3-trifluoromethyl-benzoylamino)-acetic acid (Bionet Building Blocks). Purification by HPLC gave cis and trans isomers.

WORKUP

后处理

  1. customPurification by HPLC
  2. customgave cis and trans isomers