Hydrogen chloride-ethyl acetate → HCID 86637911, compound

HRID 2389359Notes

Reaction equation

HRID 2389359 reaction equation
C(OC([NH:8][CH2:9][CH2:10][CH2:11][C:12]1[CH:24]=[CH:23][C:15]([O:16][CH2:17][C:18]([O:20][CH2:21][CH3:22])=[O:19])=[CH:14][CH:13]=1)=O)(C)(C)C.[ClH:25].CCOC(C)=O>CCOC(C)=O>[ClH:25].[NH2:8][CH2:9][CH2:10][CH2:11][C:12]1[CH:24]=[CH:23][C:15]([O:16][CH2:17][C:18]([O:20][CH2:21][CH3:22])=[O:19])=[CH:14][CH:13]=1

Participants

4

Reactant 2

HCID 21866389Hydrogen chloride-ethyl acetateHCID 86637913HCID 86637913, compound

Product 1

HCID 86637911HCID 86637911, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

To a solution of ethyl (4-{3-[(tert-butoxycarbonyl)amino]propyl}phenoxy)acetate (2.5 g) in EtOAc (7.5 mL) was added 4 M HCl/EtOAc (10 mL) at ambient temperature. After stirring for 5 hours at ambient temperature, the mixture was evaporated in vacuo to give a ethyl [4-(3-aminopropyl)phenoxy]acetate hydrochloride.

Workup

  1. customthe mixture was evaporated in vacuo

Sources & evidence

ORD record
ord-7c9af6565a4243e8838718e8daaf8d8e
Source dataset
uspto-grants-2012_09
Patent number
US08273745B2

Reaction notes

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