反应详情

6-[(2-Aminoethyl)thio]nicotinonitrile trifluoroacetate (Example 45A) is prepared in analogy to Example 40A from tert-butyl {2-[(5-cyanopyridin-2-yl)thio]ethyl}carbamate (Example 42A) (580 mg, 2.1 mmol) and trifluoroacetic acid (3.2 ml, 42 mmol) in dichloromethane (20 ml). 500 mg of the product are obtained.