反应详情

To a suspension of 80% lithium aluminum hydride (233 mg, 5.03 mmol) in tetrahydrofuran (13 mL) was added a solution of 1-(2-ethyl-8,9-dihydrofuro[3,2-c]pyrazolo[1,5-a]pyridin-1-yl)ethanone (290 mg, 1.26 mmol) in tetrahydrofuran (13 mL) under ice-cooling, and the mixture was stirred at room temperature for 1 hr. Sodium sulfate decahydrate (2.9 g) was added under ice-cooling, and the insoluble material was filtered off. The filtrate was concentrated under reduced pressure to give the title compound (265 mg, yield 90%).

1. temperaturecooling
2. temperaturecooling
3. filtrationthe insoluble material was filtered off
4. concentrationThe filtrate was concentrated under reduced pressure