反应详情

温度

50 °C

A solution of 3-bromobenzenethiol (5.00 g, 26.4 mmol) in anhydrous DMF (30 mL) was treated with K2CO3 (7.30 g, 52.8 mmol) followed by 1-bromopropane (3.90 g, 31.7 mmol) and the mixture was heated to about 50° C. under nitrogen for 12 h. The solvent was distilled out completely, and the residue was dissolved in DCM and washed with water and brine. The organic layer was dried over sodium sulphate and evaporated to afford 5.50 g (90%) of the title compound as pale yellow liquid.

1. distillationThe solvent was distilled out completely
2. dissolutionthe residue was dissolved in DCM
3. washwashed with water and brine
4. dry with materialThe organic layer was dried over sodium sulphate
5. customevaporated