4-Pyridinecarboxaldehyde → HCID 86103414, compound

HRID 239137Notes

Reaction equation

HRID 239137 reaction equation
[N:1]1[CH:6]=[CH:5][C:4]([CH:7]=O)=[CH:3][CH:2]=1.[CH2:9]([O:11][CH:12]([O:15][CH2:16][CH3:17])[CH2:13][NH2:14])[CH3:10]>C1(C)C=CC=CC=1>[CH2:9]([O:11][CH:12]([O:15][CH2:16][CH3:17])[CH2:13][N:14]=[CH:7][C:4]1[CH:3]=[CH:2][N:1]=[CH:6][CH:5]=1)[CH3:10]

Participants

4

Reactant 2

HCID 133894-PyridinecarboxaldehydeHCID 695242,2-Diethoxyethylamine

Product 1

HCID 86103414HCID 86103414, compoundYield 100%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

300 g pyridine-4-carbaldehyde and 372 g 2,2-diethoxy-ethylamine were refluxed in 2 L toluol over night. The mixture was evaporated to give 621 g of the desired product. The residue was purified by chromatographie on silica to give 100 g desired product.

Workup

  1. customThe mixture was evaporated

Sources & evidence

ORD record
ord-c7779dd223284c77b3a8b0e4e8c418c3
Source dataset
uspto-grants-2014_02
Patent number
US08642774B2

Reaction notes

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