Hydrogen Bromide → HCID 86686499, compound

HRID 239142Notes

Reaction equation

HRID 239142 reaction equation
[CH3:1][CH:2]1[CH2:8][C:7](=[O:9])[CH2:6][CH2:5][N:4](C(OC(C)(C)C)=O)[CH2:3]1.[BrH:17]>C(O)(=O)C>[BrH:17].[CH3:1][CH:2]1[CH2:3][NH:4][CH2:5][CH2:6][C:7](=[O:9])[CH2:8]1

Participants

4

Reactant 2

HCID 260Hydrogen BromideHCID 86686498HCID 86686498, compound

Product 1

HCID 86686499HCID 86686499, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent2×

Procedure

13.7 g tert-butyl 3-methyl-5-oxoazepane-1-carboxylat was dissolved in 350 mL acetic acid and 99 mL hydro bromide solution (33%) in acetic acid was added. The mixture was stirred for 1.5 h at RT. The volatiles were removed in vacuo and the residue was used in the next step without further purification. (M+H)+: 128

Workup

  1. customThe volatiles were removed in vacuo
  2. customthe residue was used in the next step without further purification

Sources & evidence

ORD record
ord-fbcb7d2178974e0180c0fa18458bf91b
Source dataset
uspto-grants-2014_02
Patent number
US08642774B2

Reaction notes

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