Potassium Bromide → HCID 18980371, compound

HRID 2392714Notes

Reaction equation

HRID 2392714 reaction equation
[Cl:1][C:2]1[C:7]([Cl:8])=[CH:6][C:5]([NH:9][C:10](=[O:19])[CH2:11][C:12]2[CH:17]=[CH:16][CH:15]=[C:14]([CH3:18])[CH:13]=2)=[C:4]([N+:20]([O-:22])=O)[CH:3]=1.[K+].[Br-]>CCO>[Cl:1][C:2]1[CH:3]=[C:4]2[C:5](=[CH:6][C:7]=1[Cl:8])[NH:9][C:10](=[O:19])[C:11]([C:12]1[CH:17]=[CH:16][CH:15]=[C:14]([CH3:18])[CH:13]=1)=[N+:20]2[O-:22]

Participants

4

Reactant 2

HCID 253877Potassium BromideHCID 67729897HCID 67729897, compound

Product 1

HCID 18980371HCID 18980371, compoundYield 97%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

The title compound was prepared according to the general procedure described in Example 6 by instituting 8 mmol of 133 for 125. Yield: 97%; mp 260°-262° C. (from EtOH); IR (KBr) 3454, 3044, 2923, 2801, 1653, 1617, 1380, 1364, 1311 and 1245 cm-1 ; 1H NMR (in DMSO-d6) δ2.31 (s, 3H), 7.23 (m, 1H,), 7.33 (m, 1H), 7.43 (m, 1H), 7.44 (s, 1H, 7.51 (s, 1H), 8.27 (s, 1H), 12.59 (br.s, 1H, N--H); HPLC: 97%; HRMS Calcd for C15H10N2O2Cl2 : 320.0119.

Sources & evidence

ORD record
ord-e7f3fa23b0674967beb9f9dc396a1559
Source dataset
uspto-grants-1998_09
Patent number
US05801183

Reaction notes

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