Dodecylamine → HCID 54004900, compound
Reaction equation
[CH2:1]([NH2:13])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12].Cl[CH2:15][CH:16]([OH:27])[CH2:17][N:18]([CH2:24][CH2:25][OH:26])[CH2:19][CH:20]([OH:23])[CH2:21]Cl>C1(C)C(C)=CC=CC=1>[OH:27][CH:16]([CH2:17][N:18]([CH2:24][CH2:25][OH:26])[CH2:19][CH:20]([OH:23])[CH2:21][NH:13][CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12])[CH2:15][NH:13][CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12]Participants
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Conditions
- Temperature
- 70 °C
Procedure
A reactor was charged with 280 g (1.51 moles) of dodecylamine and 100 g of xylene, and the contents were heated to 70° C. To the contents, a solution with 38.5 g (0.18 mole) of N,N-bis(3-chloro-2-hydroxypropyl)hydroxyethylamine dissolved in 20 g of xylene was added dropwise over 30 minutes. The resultant mixture was aged further for 4 hours. Thereafter, xylene was distilled off under reduced pressure, and unreacted dodecylamine was then distilled off at 100° C. and 0.5 mmHg. The residue was subjected to extraction and washing with a mixture of 500 ml of hexane and 500 ml of 5% aqueous sodium hydroxide. Thereafter, a hexane layer was taken out and concentrated, thereby obtaining 75.6 g (yield: 77%) of 15,19-dihydroxy-17-hydroxyethyl-13,17,21-triazatritriacontane represented by the following formula. ##STR12##
Workup
- additionwas added dropwise over 30 minutes
- distillationThereafter, xylene was distilled off under reduced pressure, and unreacted dodecylamine
- distillationwas then distilled off at 100° C.
- extractionThe residue was subjected to extraction
- washwashing with a mixture of 500 ml of hexane and 500 ml of 5% aqueous sodium hydroxide
- concentrationconcentrated
Sources & evidence
- ORD record
- ord-136deef959734decba5fd2d8a7667f80
- Source dataset
- uspto-grants-1998_09
- Patent number
- US05801270
Reaction notes
Loading…