Oxalyl chloride → 2,6-Di(propan-2-yl)benzoyl chloride

HRID 2393266Notes

Reaction equation

HRID 2393266 reaction equation
[CH:1]([C:4]1[CH:12]=[CH:11][CH:10]=[C:9]([CH:13]([CH3:15])[CH3:14])[C:5]=1[C:6](O)=[O:7])([CH3:3])[CH3:2].C(Cl)(=O)C([Cl:19])=O>CN(C)C=O>[CH:1]([C:4]1[CH:12]=[CH:11][CH:10]=[C:9]([CH:13]([CH3:15])[CH3:14])[C:5]=1[C:6]([Cl:19])=[O:7])([CH3:3])[CH3:2]

Participants

4

Reactant 2

HCID 65578Oxalyl chlorideHCID 119589902,6-diisopropylbenzoic acid

Product 1

HCID 130685852,6-Di(propan-2-yl)benzoyl chloride

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideCatalyst

Procedure

A mixture of 2,6-diisopropylbenzoic acid (12.8 g, 0.062 mol), oxalyl chloride (25 mL), and dimethylformamide (2 drops) was stirred overnight at room temperature. The volatiles were removed on the rotary evaporator and the residue dried to yield an orange oil, 12.65 g, 90.9%.

Workup

  1. customThe volatiles were removed on the rotary evaporator
  2. customthe residue dried
  3. customto yield an orange oil, 12.65 g, 90.9%

Sources & evidence

ORD record
ord-b0fb921268f647aa8967e6289c301e33
Source dataset
uspto-grants-1998_09
Patent number
US05807846

Reaction notes

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