Phosphorus oxychloride → HCID 15407842, compound

HRID 2393510Notes

Reaction equation

HRID 2393510 reaction equation
[CH:1]1[C:6]2[C:7]3[O:8][C:9]4[C:14]([O:15][C:16]=3[C:17](=O)[NH:18][C:5]=2[CH:4]=[CH:3][CH:2]=1)=[CH:13][CH:12]=[CH:11][CH:10]=4.P(Cl)(Cl)([Cl:22])=O>>[Cl:22][C:17]1[N:18]=[C:5]2[CH:4]=[CH:3][CH:2]=[CH:1][C:6]2=[C:7]2[C:16]=1[O:15][C:14]1[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=1)[O:8]2

Participants

3

Reactant 2

HCID 24813Phosphorus oxychlorideHCID 10911969HCID 10911969, compound

Product 1

HCID 15407842HCID 15407842, compound

Procedure

Under an inert atmosphere, [5H]-7,12-dioxa-5-azabenz[a]anthracen-6-one is brought to reflux of phosphorus oxychloride for 6 hours. The solvent (phosphorus oxychloride) is then evaporated off under vacuum and the crude mixture is chromatographed by flash chromatography on silica gel (eluent: petroleum ether/ethyl acetate).

Workup

  1. customThe solvent (phosphorus oxychloride) is then evaporated off under vacuum
  2. customthe crude mixture is chromatographed by flash chromatography on silica gel (eluent: petroleum ether/ethyl acetate)

Sources & evidence

ORD record
ord-4df38f854e2f4ce980fb69780e1a3713
Source dataset
uspto-grants-1998_09
Patent number
US05807882

Reaction notes

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