Tetrahydrofuran → HCID 86749480, compound

HRID 2393877Notes

Reaction equation

HRID 2393877 reaction equation
C[C:2]1([N:23]=[N+]=[N-])[O:19][C@H:18]([C:20]([OH:22])=[O:21])[C@@H:13]([O:14][C:15](=[O:17])[CH3:16])[C@H:8]([O:9][C:10](=[O:12])[CH3:11])[C@H:3]1[O:4][C:5](=[O:7])[CH3:6].[H][H].O1CCC[CH2:29]1>[Pd]>[CH3:29][NH:23][CH:2]1[O:19][C@H:18]([C:20]([OH:22])=[O:21])[C@@H:13]([O:14][C:15](=[O:17])[CH3:16])[C@H:8]([O:9][C:10](=[O:12])[CH3:11])[C@H:3]1[O:4][C:5](=[O:7])[CH3:6]

Participants

5

Reactant 3

HCID 8028TetrahydrofuranHCID 86749481HCID 86749481, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 86749480HCID 86749480, compound

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Conditions

Temperature
-15 °C

Procedure

Next, 359 mg (1 mmol) of the methyl 2,3,4-tri-O-acetyl glucopyranuronosyl azide was added to 50 ml of tetrahyrofuran containing 50 mg of 10% Pd on carbon. The solution was cooled to -15° C. and was shaken under 40 psl of hydrogen for 1 hour, filtered and concentrated to dryness to produce methyl 2,3,4,-tri-O-acetylglucopyranuronosyl amine.

Workup

  1. filtrationfiltered
  2. concentrationconcentrated to dryness

Sources & evidence

ORD record
ord-cae1f3287a8c4e04be7a94492debe84a
Source dataset
uspto-grants-1998_09
Patent number
US05808111

Reaction notes

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