Potassium Carbonate → HCID 15334456, compound

HRID 2394287Notes

Reaction equation

HRID 2394287 reaction equation
Cl[C:2]1[C:7]([C:8]([C:10](=[CH:16][NH:17][CH:18]2[CH2:20][CH2:19]2)[C:11]([O:13][CH2:14][CH3:15])=[O:12])=[O:9])=[CH:6][N:5]=[C:4]([Cl:21])[C:3]=1[Cl:22].C(=O)([O-])[O-].[K+].[K+]>CN(C=O)C>[Cl:21][C:4]1[C:3]([Cl:22])=[C:2]2[C:7]([C:8](=[O:9])[C:10]([C:11]([O:13][CH2:14][CH3:15])=[O:12])=[CH:16][N:17]2[CH:18]2[CH2:20][CH2:19]2)=[CH:6][N:5]=1

Participants

4

Reactant 2

HCID 11430Potassium CarbonateHCID 178471896HCID 178471896, compound

Product 1

HCID 15334456HCID 15334456, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

17.5 g (0.048 mol) of ethyl 2-(4,5,6-trichloronicotinoyl)-3-cyclopropylamino-acrylate are heated with 7.7 g (0.056 mol) of potassium carbonate in 100 ml of DMF at 60° C. for two hours. Ice-water is added to the cooled mixture, and the product is isolated.

Workup

  1. customthe product is isolated

Sources & evidence

ORD record
ord-3fb1b0ec1b7441068e66c49834f69904
Source dataset
uspto-grants-1998_09
Patent number
US05811433

Reaction notes

Loading…