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HRID2394477

反应详情

EQUATION

反应方程式

HRID 2394477 的结构方程式

REACTANTS

反应物

2
结构：CN=C=S
HCID11167

Methyl isothiocyanate

C2H3NS

结构：COc1ccc(Cl)cc1C(=O)NCC1CCOc2cc(OC)c(S(N)(=O)=O)cc21
HCID11048464

未命名化合物

PRODUCTS

生成物

1
结构：CNC(=S)NS(=O)(=O)c1cc2c(cc1OC)OCCC2CNC(=O)c1cc(Cl)ccc1OC
HCID9871110

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CN(C)C=O
溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

PROCEDURE

实验过程

(-)-4-(5-Chloro-2-methoxybenzamidomethyl)-6-(methylaminothiocarbonylaminosulfonyl)-7-methoxychroman ##STR61## (-)-4-(5-Chloro-2-methoxybenzamidomethyl)-6-(methylaminothiocarbonyl-aminosulfonyl)-7-methoxychroman is prepared as described in Example 4 from optically active 4-(5-chloro-2-methoxybenzamidomethyl)-6-sulfamoyl-7-methoxychroman and methyl isothiocyanate. Melting point: 202° C., [α]D20 : -64.5° (c=1, DMF); HPLC: ee 97.9%.