Hydrochloric Acid → HCID 54421939, compound

HRID 2395594Notes

Reaction equation

HRID 2395594 reaction equation
[ClH:1].[CH:2]([CH:4]([C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([C:12]([F:15])([F:14])[F:13])[C:7]=1[F:16])O)=[CH2:3]>O1CCOCC1>[Cl:1][CH2:3][CH:2]=[CH:4][C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([C:12]([F:15])([F:14])[F:13])[C:7]=1[F:16]

Participants

4

Reactant 2

HCID 313Hydrochloric Acid2×HCID 18989445HCID 18989445, compound

Product 1

HCID 54421939HCID 54421939, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

334 ml of concentrated HCl are added over 10 minutes to a solution of 404.5 g (1.84 mol) of α-ethenyl-2-fluoro-3-(trifluoromethyl)benzenemethanol (prepared according to Example I1) in 3.7 1 of dioxane and the mixture is then heated for 2 h at reflux. 83.5 ml of concentrated HCl are added and the mixture is heated for a further 2 h at reflux.

Workup

  1. temperaturethe mixture is then heated for 2 h
  2. temperatureat reflux
  3. temperaturethe mixture is heated for a further 2 h
  4. temperatureat reflux

Sources & evidence

ORD record
ord-bd32231425bc4ed99f329d736c1e1016
Source dataset
uspto-grants-1996_02
Patent number
US05489592

Reaction notes

Loading…