4-Phenyl-2-butanol → (3-Fluorobutyl)benzene

HRID 2397086Notes

Reaction equation

HRID 2397086 reaction equation
CC(O)CCc1ccccc1.O=S(=O)(F)c1ccc(C(F)(F)F)cc1>C1CCC2=NCCCN2CC1.C1CCOC1>CC(F)CCc1ccccc1

Participants

5

Reactant 2

HCID 613024-Phenyl-2-butanolHCID 858282354-(Trifluoromethyl)benzenesulfonyl fluoride

Product 1

HCID 14870238(3-Fluorobutyl)benzeneYield 52%

Reagents, catalysts & solvents 2

HCID 811841,8-Diazabicyclo(5.4.0)undec-7-eneReagentHCID 8028TetrahydrofuranSolvent2×

Workup

  1. additionNo procedure recorded

Sources & evidence

ORD record
ord-8b250f79c11047c18fc354b270784b16
Source dataset
Deoxyfluorination screen
Original link
View source

Reaction notes

Loading…