Cyclohexylamine → HCID 21437961, compound

HRID 2397417Notes

Reaction equation

HRID 2397417 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([C:8]2[CH:13]=[CH:12][C:11]([C:14](=[O:20])[CH2:15][CH2:16][C:17]([OH:19])=[O:18])=[CH:10][CH:9]=2)[CH:5]=[CH:6][CH:7]=1.C1(N)CCCCC1.C(OCC)(=O)C>CO>[Cl:1][C:2]1[CH:3]=[C:4]([C:8]2[CH:13]=[CH:12][C:11]([CH:14]([OH:20])[CH2:15][CH2:16][C:17]([OH:19])=[O:18])=[CH:10][CH:9]=2)[CH:5]=[CH:6][CH:7]=1

Participants

5

Reactant 3

HCID 7965CyclohexylamineHCID 8857Ethyl AcetateHCID 230052373′-Chloro-γ-oxo[1,1′-biphenyl]-4-butanoic acid

Product 1

HCID 21437961HCID 21437961, compoundYield 65%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Prepared analogous to Example 25 from 4-(3'-chloro-4-biphenylyl)-4-oxo-butyric acid. Melting point of the cyclohexylamine salt: 160°-161° C. (from ethyl acetate by addition of methanol). Yield: 65% of theory.

Sources & evidence

ORD record
ord-55c3bd4b006e46339b7dcb3bd8e6eb76
Source dataset
uspto-grants-1977_05
Patent number
US04021479

Reaction notes

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