Methylamine → N-Methyl-D-glucamine

HRID 2397427Notes

Reaction equation

HRID 2397427 reaction equation
[O:1]=[CH:2][C@@H:3]([C@H:5]([C@@H:7]([C@@H:9]([CH2:11]O)[OH:10])[OH:8])[OH:6])[OH:4].[CH3:13][NH2:14]>>[CH3:13][NH:14][CH2:11][C@@H:9]([C@H:7]([C@@H:5]([C@@H:3]([CH2:2][OH:1])[OH:4])[OH:6])[OH:8])[OH:10]

Participants

3

Reactant 2

HCID 6329MethylamineHCID 107526(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal

Product 1

HCID 8567N-Methyl-D-glucamine

Procedure

The product was made from D-glucose and methylamine comparable as in Example A. A crystallized colorless product with a melting point of 127° to 128° C. was obtained.

Workup

  1. customA crystallized colorless product with a melting point of 127° to 128° C. was obtained

Sources & evidence

ORD record
ord-b54a438ad66a40739b147272722be53b
Source dataset
uspto-grants-1977_05
Patent number
US04021539

Reaction notes

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