反应详情

A suspension of 3-(2-furyl)-5-(4-nitrophenyl)-1,2,4-oxadiazole (8.0 g, 0.03 mole) in 200 ml of absolute alcohol containing 5.2 ml of concentrated HCl is hydrogenated using 0.5 g of 5% Pd on carbon as catalyst. The solid obtained is slurried with saturated K2CO3 solution and extracted with CHCl3. Evaporation of the CHCl3 in vacuo gives the amine, 5.1 g (72%), m.p. 183°-185° .

1. customThe solid obtained
2. extractionextracted with CHCl3
3. customEvaporation of the CHCl3 in vacuo