Methylamine → HCID 178484394, compound

HRID 2398260Notes

Reaction equation

HRID 2398260 reaction equation
[NH2:1][CH2:2][CH2:3][CH2:4][CH2:5][C:6]1[N:7]=[CH:8][NH:9][CH:10]=1.[N+](C=C(SC)SC)([O-])=O.[N+:20]([CH:23]=[C:24](SC)[NH:25][CH2:26]CCCC1N=CNC=1)([O-:22])=[O:21].CN>>[N+:20]([CH:23]=[C:24]([NH:25][CH3:26])[NH:1][CH2:2][CH2:3][CH2:4][CH2:5][C:6]1[N:7]=[CH:8][NH:9][CH:10]=1)([O-:22])=[O:21]

Participants

5

Reactant 4

HCID 6329MethylamineHCID 836231,1-Bis(methylthio)-2-nitroethyleneHCID 1785038211-Nitro-2-methylthio-2-[4-(4-imidazolyl)butylamino]ethyleneHCID 178510959HCID 178510959, compound

Product 1

HCID 178484394HCID 178484394, compound

Procedure

Reaction of 4-(4-aminobutyl)imidazole (from the dihydrobromide (3.6 g)) with 1-nitro-2,2-bis-methylthioethylene (2.0 g) by the procedure of Example 4(i) and treatment of the resultant 1-nitro-2-methylthio-2-[4-(4-imidazolyl)butylamino]ethylene with methylamine according to the procedure of Example 3(ii) gives the title compound.

Sources & evidence

ORD record
ord-b296e926ea0c4be6a1f23703e9370df3
Source dataset
uspto-grants-1977_05
Patent number
US04024260

Reaction notes

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