HCID 68118800, compound → HCID 68119677, compound

HRID 2398567Notes

Reaction equation

HRID 2398567 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([CH3:10])=[C:6]([N:11]2[C:15](=[O:16])[C:14]3=[CH:17][C:18]([C:21](=[O:23])[NH2:22])=[CH:19][CH:20]=[C:13]3[C:12]2=[O:24])[CH:5]=1)([O-])=O>[Pt]=O.C(OCC)(=O)C>[NH2:1][C:4]1[CH:9]=[CH:8][C:7]([CH3:10])=[C:6]([N:11]2[C:15](=[O:16])[C:14]3=[CH:17][C:18]([C:21](=[O:23])[NH2:22])=[CH:19][CH:20]=[C:13]3[C:12]2=[O:24])[CH:5]=1

Participants

4

Reactant 1

HCID 68118800HCID 68118800, compound

Product 1

HCID 68119677HCID 68119677, compound

Reagents, catalysts & solvents 2

HCID 82844Platinum oxide (PtO)CatalystHCID 8857Ethyl AcetateSolvent

Procedure

The mixture of 1.5 g of N-(4-nitro-o-tolyl)-4-carbamoylphthalimide 200 ml of ethyl acetate and 0.3 g of platinum oxide is hydrogenated at 2.5 atm. and about 40° for 50 minutes. It is filtered, the filtrate concentrated and the precipitate collected, to yield the N-(4-amino-o-tolyl)-4-carbamoylphthalimide melting at 240°-242°.

Workup

  1. filtrationIt is filtered
  2. concentrationthe filtrate concentrated
  3. customthe precipitate collected

Sources & evidence

ORD record
ord-9a2d36da408648bfb0140edc3085b26e
Source dataset
uspto-grants-1977_05
Patent number
US04025505

Reaction notes

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